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KMID : 0191120160310121969
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Journal of Korean Medical Science
2016 Volume.31 No. 12 p.1969 ~ p.1975
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Development and Validation of the Korean Version of Hand-Foot Skin Reaction and Quality of Life Questionnaire (HF-QoL-K)
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Nam Se-Hyun
Choi Hyun-Jin
Kang Woo-Dae
Kim Seok-Mo
Lim Myong-Cheol
Park Sang-Yoon
Kim Jung-Sup
Kim Byoung-Gie
Bae Duk-Soo
Lee Jeong-Won
Kim Tae-Joong
Song Tae-Jong
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Abstract
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Given the growing number of cancer patients and the resulting increase in the administration of chemotherapeutic agents, convenient and effective methods for measuring the symptoms and quality of life associated with the hand-foot syndrome (HFS) are needed. Therefore, the aim of this study was to develop and validate the Korean version of the hand-foot skin reaction and quality of life questionnaire (HF-QoL-K), comprising a 20-item symptom domain and an 18-item daily activity domain. After we developed the HF-QoL-K, 209 Korean patients with gynecologic cancer who were undergoing chemotherapeutic agents relating the HFS were asked to fill in the questionnaire. The content validity, internal consistency reliability, and test-retest reliability were evaluated. The internal validity index, Cronbach’s alpha coefficient, and intra-class correlation coefficient of the HF-QoL-K were 0.90, 0.958, and 0.825 (95% confidence interval [CI], 0.774?0.865), respectively. The scatter plot (Pearson correlation coefficient, 0.826) and the Bland-Altman plot for test-retest reliability were also acceptable. The HF-QoL-K instrument is a valid and reliable questionnaire for the measurement of the symptoms and quality of life in Korean cancer patients suffering HFS.
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KEYWORD
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Hand-Foot Syndrome, Quality of Life, Questionnaires, Validation, Gynecologic Cancer, Chemotherapy
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